文件待客户提供
说明书COAMSDS
Recombinant Human CD2 Protein, Avi-His
CD2 (also termed LFA-2, SRBC receptor) is a type I single-pass transmembrane protein of the immunoglobulin superfamily, expressed on T and NK cells. Its extracellular region comprises one IgV-type and one IgC2-type domain. CD2 binds human CD58 (LFA-3) or rodent CD48, mediating cell adhesion and providing co-stimulatory signals for T and NK cells. As a specific biomarker of T/NK cells, CD2 is applied in immunohistochemistry for tissue detection of these cells.
| 分子别名（Synonyms） | CD2, SRBC, LFA-2, T11 |
|---|---|
| 蛋白结构及表达系统（Protein Construction ＆ Source） | ·(Uniprot: P06729) Recombinant Human CD2 Protein is expressed from HEK293 cells with Avi-His tag at the C-terminus. It containsAA Lys 25 - Asp 209. ·The protein has a predicted MW of 24.8 kDa. The protein migrates as 35-45 kDa when calibrated against under reducing (R) condition (SDS-PAGE) due to glycosylation.. |
| 内毒素（Endotoxin） | < 0.1 EU per ug as determined by the LAL method. |
| 纯度（Purity） | > 90 % as determined by SDS-PAGE. |
| 浓度及缓冲液（Concentration ＆ Formulation） | ·1.8 mg/mL·Filtered through a 0.22 μm filter, stored in 1x PBS, pH 7.4. |
| 运输及储存（Transportation ＆ Storage） | ·This product is shipped under low-temperature conditions. Avoid repeated freeze-thaw cycles during handling. ·Protein solution can be stored at 2-8°C for 2-7 days. ·Samples are stable for 3 months from date of receipt at -20℃ /-80℃. ·Recommend to aliquot the protein into smaller quantities for optimal storage. |
| 靶点背景 | CD2 (also termed LFA-2, SRBC receptor) is a type I single-pass transmembrane protein of the immunoglobulin superfamily, expressed on T and NK cells. Its extracellular region comprises one IgV-type and one IgC2-type domain. CD2 binds human CD58 (LFA-3) or rodent CD48, mediating cell adhesion and providing co-stimulatory signals for T and NK cells. As a specific biomarker of T/NK cells, CD2 is applied in immunohistochemistry for tissue detection of these cells. |
|---|
仅供科研使用。不可用于临床诊断、治疗或人体。
告诉我们预期应用与现有起始材料，我们会评估可行性、匹配合适的技术路线，并给出定制报价，通常一个工作日内由科学家直接回复。
